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What is Zhewitra 10 Mg mechanism of action?
What is Zhewitra 10 Mg mechanism of action?
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kirazmattson
439 posts
Mar 21, 2025
1:36 AM
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Zhewitra 10 mg contains Vardenafil, which is a PDE5 inhibitor (phosphodiesterase type 5 inhibitor). It is primarily used to treat erectile dysfunction (ED) in men. The mechanism of action of Vardenafil (the active ingredient in Zhewitra) is similar to other PDE5 inhibitors, such as Sildenafil (Viagra) and Tadalafil (Cialis), but with some differences in how long the drug works. Mechanism of Action of Zhewitra 10 mg (Vardenafil): Inhibition of PDE5 enzyme: PDE5 is an enzyme found in the smooth muscle cells of the penis, where it breaks down cyclic guanosine monophosphate (cGMP). cGMP is a molecule that helps relax smooth muscles and dilate blood vessels. Vardenafil inhibits the action of the PDE5 enzyme, preventing it from breaking down cGMP. Increased cGMP Levels: When the breakdown of cGMP is inhibited, its levels increase in the smooth muscle cells of the penis. Higher cGMP levels lead to the relaxation of smooth muscle and dilation of the blood vessels (vasodilation). Enhanced Blood Flow: The relaxation of smooth muscle and dilation of blood vessels allows more blood to flow into the corpora cavernosa (the erectile tissue of the penis). This results in an erection when the individual Zhewitra 10 Mg sexually aroused. Effect on Erection: Vardenafil enhances the natural erectile response to sexual stimulation. However, it does not cause an erection without sexual arousal. It simply improves the ability to maintain an erection when stimulated. Important Considerations: Onset of Action: Zhewitra typically takes about 30 to 60 minutes to start working, with its effects lasting for 4-6 hours. Sexual Stimulation Required: Zhewitra does not work without sexual arousal. It only helps facilitate an erection in response to sexual stimulation. Dose: Zhewitra is typically started at 10 mg, but it can be adjusted based on individual response and tolerability, with the maximum recommended dose being 20 mg.
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